A dormant sub-population expressing interleukin-1 receptor characterises anti-estrogen resistant ALDH+ breast cancer stem cells
A. Sarmiento-Castro, E. Caamano-Gutierrez, A. Sims, M. I. James, A. Santiago-Gomez, R. Eyre, C. Clark, M. E. Brown, M. D. Brooks, D. F. Hayes, M. S. Wicha, S. J. Howell, R. Clarke, B. M. Simoes
The paper identifies a dormant ALDH+IL1R1+ sub-population in anti-estrogen resistant breast cancer stem cells and links IL1R1 expression to treatment failure.
bioRxiv · Oct 29, 2019Cancer Biology