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2 papers
Recent·Most cited
M. Dedenon, J. Barbazan, C. Perez Gonzalez, D. Vignjevic, P. Sens
This study shows that frictional forces from cancer-associated fibroblasts induce budding in cancer cell monolayers through a purse-string mechanism, driven by a supracellular contractile ring.
bioRxiv · Feb 26, 2024Biophysics
J. Barbazan, C. Perez-Gonzalez, M. Gomez-Gonzalez, M. Dedenon, S. Richon, E. Latorre, M. Serra, P. Mariani, S. Descroix, P. Sens, X. Trepat, D. Matic-Vignjevic
This study shows cancer-associated fibroblasts actively compress cancer cells via actomyosin contractility, altering YAP localization and tumor morphology.
bioRxiv · Apr 5, 2021Cell Biology