Author

J. Barbazan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Perez-Gonzalez· 2 shared M. Dedenon· 2 shared P. Sens· 2 shared A. Goel· 1 shared A. Herbette· 1 shared A. Illand· 1 shared A. Latouche· 1 shared A. Nicolas· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

C. Perez-Gonzalez

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Friction-induced budding of a cancer cell monolayer

M. Dedenon, J. Barbazan, C. Perez Gonzalez, D. Vignjevic, P. Sens

This study shows that frictional forces from cancer-associated fibroblasts induce budding in cancer cell monolayers through a purse-string mechanism, driven by a supracellular contractile ring.

bioRxiv · Feb 26, 2024Biophysics

Fibroblasts generate topographical cues that steer cancer cell migration

F. Baschieri, A. Illand, J. Barbazan, O. Zajac, C. Henon, D. Loew, F. Dingli, D. Matic Vignjevic, S. Leveque-Fort, G. Montagnac

This study shows fibroblasts create tubular structures that guide cancer cell migration by acting as physical tracks.

bioRxiv · Sep 6, 2022Cancer Biology

Low centrosome numbers correlate with higher aggressivity in ovarian cancer

J.-P. Morretton, A. Simon, A. Herbette, J. Barbazan, C. Perez-Gonzalez, C. Cosson, B. Mboup, A. Latouche, T. Popova, Y. Kieffer, P. Gestraud, G. Bataillon, V. Becette, D. Meseure, A. Nicolas, , R. Basto

The paper analyzes centrosome numbers in ovarian cancers and finds that low centrosome numbers correlate with poor patient survival and mesenchymal subgroup enrichment.

bioRxiv · Jan 4, 2022 · PreprintCancer Biology

Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction

J. Barbazan, C. Perez-Gonzalez, M. Gomez-Gonzalez, M. Dedenon, S. Richon, E. Latorre, M. Serra, P. Mariani, S. Descroix, P. Sens, X. Trepat, D. Matic-Vignjevic

This study shows cancer-associated fibroblasts actively compress cancer cells via actomyosin contractility, altering YAP localization and tumor morphology.

bioRxiv · Apr 5, 2021Cell Biology

Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors

Y. Dunkel, J. Ear, Y. Mittal, B. Lim, L. Liu, M. Holda, U. Nitsche, J. Barbazan, A. Goel, K.-P. Janssen, N. Aznar, P. Ghosh

The paper identifies two Daple/CCDC88C isoforms, showing they cooperatively suppress tumor growth but only the full-length isoform triggers EMT and invasion, with aspirin affecting their expression.

bioRxiv · May 2, 2018Cancer Biology