Author

M. E. Klotman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Organism:non-human primate· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Cara· 2 shared C. LaBranche· 2 shared D. Negri· 2 shared M. Blasi· 2 shared A. Canitano· 1 shared A. Ciarla· 1 shared A. Gallinaro· 1 shared A. M. Moody· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Cara

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2 papers

Recent·Most cited

Persistent Immunogenicity of Integrase Defective Lentiviral Vectors delivering membrane tethered Native-Like HIV-1 Envelope Trimers

A. Gallinaro, M. F. Pirillo, Y. Aldon, S. Cecchetti, Z. Michelini, A. Tinari, M. Borghi, A. Canitano, P. F. McKay, R. Bona, M. F. Vescio, F. Grasso, M. Blasi, S. Baroncelli, G. Scarlatti, , A. Cara

This study shows that IDLV vectors with membrane-tethered native-like HIV-1 Env trimers induce faster and longer-lasting anti-Env IgG responses in mice and macaques, with some animals developing neutralization activity against HIV-1.

bioRxiv · Oct 8, 2021Immunology

Immunogenicity, safety and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs

M. Blasi, D. Negri, K. O. Saunders, E. J. Baker, H. Stadtler, C. LaBranche, B. Mildenberg, G. Morton, A. Ciarla, X. Shen, Y. Wang, W. Rountree, B. Balakumaran, S. Santra, B. F. Haynes, , M. E. Klotman

This study evaluates an SIV-based IDLV vaccine expressing sequential CH505 Envs in rhesus macaques, showing improved antibody responses and virus control but no broadly neutralizing antibodies.

bioRxiv · Mar 6, 2020Immunology