Author

M. E. Zegans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

E. G. Romanowski· 2 shared H. Q. Shanks· 2 shared R. M. Q. Shanks· 2 shared A. Mammen· 1 shared A. S. Grewel· 1 shared B. S. Ross· 1 shared C. G. Perez· 1 shared C. V. Sundar-Raj· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

E. G. Romanowski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cefiderocol: A new and effective topical monotherapy treatment for experimental extensively-drug resistant Pseudomonas aeruginosa keratitis

E. G. Romanowski, S. M. Mumpers, H. Q. Shanks, K. A. Yates, J. B. Mandell, M. E. Zegans, R. M. Q. Shanks

This study tests cefiderocol as a topical treatment for XDR Pseudomonas aeruginosa keratitis, showing it is effective in vitro and in vivo against an XDR isolate.

bioRxiv · Aug 31, 2023 · PreprintMicrobiology

Rise in frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

R. M. Q. Shanks, S. Atta, N. A. Stella, C. V. Sundar-Raj, J. E. Romanowski, A. S. Grewel, H. Q. Shanks, S. M. Mumper, D. K. Dhaliwal, A. Mammen, J. D. Callaghan, R. C. Calvario, E. G. Romanowski, R. P. Kowalski, M. E. Zegans, V. Jhanji

The paper tracks the rise in lasR mutations in Pseudomonas aeruginosa keratitis isolates from 1993 to 2021, showing increased frequency and association with worse clinical outcomes.

bioRxiv · Aug 22, 2023 · PreprintMicrobiology

Antifungal activity of Propranolol against Fusarium keratitis isolates from the Mycotic Ulcer Treatment Trial (MUTT) and the United States.

R. Bao, B. S. Ross, C. G. Perez, G. Poimenidou, N. V. Prajna, R. A. Cramer, M. E. Zegans

This study evaluates the antifungal activity of propranolol and its enantiomers against Fusarium keratitis isolates and Aspergillus fumigatus, finding fungicidal effects and reduced MIC with natamycin.

bioRxiv · Jan 19, 2021 · PreprintMicrobiology