Author

I. C. Cirstea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. V. Busley· 2 shared L. Cyganek· 2 shared M. R. Ahmadian· 2 shared A. Borchardt· 1 shared A. Hahn· 1 shared A. Mirzaiebadizi· 1 shared A. Reichert· 1 shared A. Schaenzer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A. V. Busley

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

A. V. Busley, O. Gutierrez-Gutierrez, E. Hammer, F. Koitka, A. Mirzaiebadizi, M. Steinegger, C. Pape, L. Boehmer, H. Schroeder, M. Kleinsorge, M. Engler, I. C. Cirstea, L. Gremer, D. Willbold, J. Altmueller, , L. Cyganek

This study identifies a novel LZTR1 variant causing cardiac hypertrophy by altering protein polymerization and ubiquitin ligase function, showing genetic correction can rescue the phenotype.

bioRxiv · Jan 10, 2023Cell Biology

Alteration of myocardial structure and function in RAF1associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs

S. Nakhaei-Rad, F. Bazgir, J. Dahlmann, A. V. Busley, M. Buchholzer, F. Haghighi, A. Schaenzer, A. Hahn, S. Koetter, D. Schanze, R. Anand, F. Funk, A. Borchardt, A. V. Kronenbitter, J. Scheller, , M. R. Ahmadian

This study uses patient-derived iPSCs to model RAF1-associated Noonan syndrome and identifies sarcomere structural abnormalities linked to cardiac dysfunction.

bioRxiv · Jan 22, 2022 · PreprintCell Biology