Author

M. F. Jennewein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:multiome· 1

Frequent Co-Authors

A. Gerhardt· 2 shared A. T. McGuire· 2 shared C. Casper· 2 shared D. Hanson· 2 shared E. A. Voigt· 2 shared J. Bakken· 2 shared J. Singh· 2 shared L. J. Homad· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Gerhardt

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission

M. F. Jennewein, M. D. Schultz, S. Beaver, P. Battisti, J. Bakken, D. Hanson, J. Akther, F. Zhou, R. Mohamath, J. Singh, N. Cross, D. N. Kasal, M. Ykema, S. Reed, D. Kalange, , E. A. Voigt

This study compares intranasal and intramuscular delivery of a self-amplifying RNA SARS-CoV-2 vaccine, showing that intranasal delivery induces mucosal immunity and reduces viral transmission.

bioRxiv · Nov 10, 2022 · PreprintImmunology

A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability

E. A. Voigt, A. Gerhardt, D. Hanson, P. Battisti, S. Reed, J. Singh, R. Mohamath, M. F. Jennewein, J. Bakken, S. Beaver, C. Press, P. Soon-Shiong, C. J. Paddon, C. B. Fox, C. Casper

This paper develops a self-amplifying RNA vaccine against SARS-CoV-2 with room-temperature stability and strong immune responses in preclinical studies.

bioRxiv · Mar 22, 2022Immunology

Functional and structural modifications of influenza antibodies during pregnancy

M. F. Jennewein, M. Kosikova, F. J. Noelette, P. Radvak, C. M. Boudreau, J. D. Campbell, W. H. Chen, H. Xie, G. Alter, M. F. Pasetti

This study examines how influenza antibodies change structurally and functionally during pregnancy, showing reduced inflammation and increased antibody retention.

bioRxiv · May 18, 2021Immunology

Designed proteins assemble antibodies into modular nanocages

R. Divine, H. V. Dang, G. Ueda, J. A. Fallas, I. Vulovic, W. Sheffler, S. Saini, Y. T. Zhao, I. X. Raj, P. A. Morawski, M. F. Jennewein, L. J. Homad, Y.-H. Wan, M. R. Tooley, F. Seeger, , D. Baker

The paper designs modular nanocages that assemble antibodies into precise geometries, enhancing signaling and neutralization compared to free antibodies.

bioRxiv · Dec 1, 2020Biochemistry

Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

E. Seydoux, L. J. Homad, A. J. MacCamy, K. R. Parks, N. K. Hurlburt, M. F. Jennewein, N. R. Akins, A. B. Stuart, Y.-H. Wan, J. Feng, R. Nelson, S. Singh, K. W. Cohen, J. M. McElrath, J. A. Englund, , L. Stamatatos

This study characterizes neutralizing antibodies from a SARS-CoV-2 infected individual, finding that most antibodies are non-neutralizing and target epitopes outside the RBD, while two potent neutralizers bind the RBD with minimal mutation.

bioRxiv · May 12, 2020 · PreprintImmunology