Author

M. Falchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

A. C. Dueck· 1 shared A. De Ninno· 1 shared A. Peli· 1 shared A. Possenti· 1 shared A. R. Migliaccio· 1 shared A. Visconti· 1 shared C. I. Le Roy· 1 shared C. Mead-Harvey· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. C. Dueck

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells

F. Noto, A. De Ninno, M. Falchi, L. Businaro, G. Schiavoni, F. Mattei

The paper presents a microfluidic organ-on-chip method to study immune cell responses to drug-treated tumor cells in 3D.

bioRxiv · Apr 24, 2024 · PreprintCancer Biology

GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis

F. Gobbo, M. Zingariello, P. Verachi, M. Falchi, F. Arciprete, F. Martelli, A. Peli, M. Mazzarini, J. Vierstra, C. Mead-Harvey, A. C. Dueck, G. Sarli, S. Nava, G. Sgalla, L. Richeldi, A. R. Migliaccio

The paper identifies GATA1-defective immune-megakaryocytes in IPF patients and mice, showing their role in lung fibrosis through TGF-β1, CXCL1, and P-selectin mechanisms.

bioRxiv · Jun 20, 2023 · PreprintImmunology

Functional characterization of the thrombospondin-related paralogous proteins rhoptry discharge factor 1 and 2 unveils phenotypic plasticity in Toxoplasma gondii rhoptry exocytosis

A. Possenti, M. Di Cristina, C. Nicastro, M. Lunghi, V. Messina, F. Piro, L. Tramontana, S. Cherchi, M. Falchi, L. Bertuccini, F. Spano

This study identifies and characterizes RDF1 and RDF2, two T. gondii proteins essential for rhoptry exocytosis, revealing a compensatory mechanism that contributes to phenotypic plasticity.

bioRxiv · Mar 2, 2022Microbiology

Interplay between the human gut microbiome and host metabolism

A. Visconti, C. I. Le Roy, F. Rosa, N. Rossi, T. C. Martin, R. P. Mohney, L. Weizhong, E. de Rinaldis, J. T. Bell, J. C. Venter, K. E. Nelson, T. D. Spector, M. Falchi

This study examines the gut microbiome's metabolic interactions with the host, finding that functional pathways, not just species, significantly influence metabolites in blood and feces.

bioRxiv · Feb 27, 2019Microbiology

M. Falchi · henhao