M. G. Dieterle

Intestinal inflammation and altered gut microbiota associated with inflammatory bowel disease renders mice susceptible to Clostridioides difficile colonization and infection

This study shows that intestinal inflammation and altered gut microbiota in IBD make mice susceptible to C. difficile colonization and infection, highlighting the role of IBD-induced microbiota in disease severity.

Aging dampens the intestinal innate immune response during Clostridioides difficile infection and is associated with altered intestinal eosinophil mobilization

This study shows that aging impairs the intestinal innate immune response to C. difficile infection, leading to increased disease severity and altered eosinophil mobilization.