Author

M. G. Duval

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. McAlary· 2 shared S. S. Plotkin· 2 shared W. T. Allison· 2 shared A. Dijkstra· 1 shared A. Y. Roman· 1 shared E. Pokrishevsky· 1 shared J.-P. Julien· 1 shared M. Habibi· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

L. McAlary

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2 papers

Recent·Most cited

Tryptophan residues in TDP-43 and SOD1 mediate the cross-seeding and toxicity of SOD1

E. Pokrishevsky, M. G. Duval, L. McAlary, S. Louadi, S. Pozzi, A. Y. Roman, S. S. Plotkin, A. Dijkstra, J.-P. Julien, W. T. Allison, N. R. Cashman

This study identifies tryptophan residues in SOD1 and TDP-43 that mediate cross-seeding and toxicity in ALS, suggesting a druggable target for therapeutic intervention.

bioRxiv · Jul 27, 2020 · PreprintCell Biology

In Silico Determined Properties of Designed Superoxide Dismutase-1 Mutants Predict ALS-like Phenotypes In Vitro and In Vivo

M. G. DuVal, L. McAlary, M. Habibi, P. Garg, M. Sher, N. Cashman, W. T. Allison, S. S. Plotkin

The paper designs and tests SOD1 mutants using computational methods, showing that a destabilizing mutant causes ALS-like phenotypes while a stabilizing mutant rescues them in zebrafish.

bioRxiv · Nov 21, 2018 · PreprintBiophysics