Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti
Y. Saucereau, T. H. Wilson, M. C. , K. Tang, M. C. Moncrieffe, S. W. Hardwick, D. Y. Chirgadze, S. G. Soares, M. J. Marcaida, N. J. Gay, M. Gangloff
The paper presents cryo-EM structures of Toll5A and Spaetzle1C complexes in Aedes aegypti, revealing their asymmetric interactions and distinct transcriptional roles in immune response.
bioRxiv · Sep 6, 2021Immunology