Author

M. C. Moncrieffe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:cryo-EM· 1

Frequent Co-Authors

N. J. Gay· 2 shared S. G. Soares· 2 shared B. B. Kaufer· 1 shared B. Kaspers· 1 shared D. Y. Chirgadze· 1 shared H.-G. Rammensee· 1 shared J. E. J. Holm· 1 shared J. Kaufman· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

N. J. Gay

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Author profile →

3 papers

Recent·Most cited

Anterograde Trafficking of Toll-Like Receptors Requires the Cargo Sorting Adaptors TMED-2 and 7 and specific N-glycans

N. J. Gay, S. G. Soares, M. C. Moncrieffe, J. E. J. Holm, M. F. Symmons

This study identifies TMED2 and TMED7 as cargo sorting adaptors required for TLR trafficking from the ER to Golgi, with specific N-glycans on TLR2 playing a role in this process.

bioRxiv · Oct 10, 2022 · PreprintCell Biology

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Y. Saucereau, T. H. Wilson, M. C. , K. Tang, M. C. Moncrieffe, S. W. Hardwick, D. Y. Chirgadze, S. G. Soares, M. J. Marcaida, N. J. Gay, M. Gangloff

The paper presents cryo-EM structures of Toll5A and Spaetzle1C complexes in Aedes aegypti, revealing their asymmetric interactions and distinct transcriptional roles in immune response.

bioRxiv · Sep 6, 2021Immunology

Differential host response to a herpesvirus: Mareks disease virus peptides on chicken MHC class II molecules are derived from only a few genes and illustrate a new mode of peptide binding

S. Halabi, M. Ghosh, S. Stevanovic, H.-G. Rammensee, L. D. Bertzbach, B. B. Kaufer, M. C. Moncrieffe, B. Kaspers, S. Härtle, J. Kaufman

The paper identifies that Mareks disease virus peptides presented by chicken MHC class II molecules come from only four genes, revealing a new peptide binding mode and explaining MHC-driven resistance to the virus.

bioRxiv · Nov 27, 2020Immunology