Author

M. Guerau-de-Arellano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

S. A. Amici· 2 shared S. Sengupta· 2 shared A. Kennemer· 1 shared A. Khan· 1 shared B. W. Lewis· 1 shared C. Edell· 1 shared E. Shalosky· 1 shared G. Laliotis· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

S. A. Amici

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Author profile →

3 papers

Recent·Most cited

ImmunologyImmunoHorizonsPeer-reviewedOct 29, 2021

PRMT5 promotes symmetric dimethylation of RNA processing proteins and modulates activated T cell alternative splicing and Ca2+/NFAT signaling

S. Sengupta, K. O. West, S. Sanghvi…·M. Guerau-de-Arellano

This study identifies PRMT5's role in modulating alternative splicing and Ca2+/NFAT signaling in activated T cells through symmetric dimethylation of RNA processing proteins.

DOI 10.4049/immunohorizons.2100076

mouseproteomics

𝕏 PostBluesky

ImmunologybioRxivOct 13, 2021

PRMT5 in T cells drives Th17 responses, mixed granulocytic inflammation and severe allergic airway inflammation

B. W. Lewis, S. A. Amici, H.-Y. Kim…·M. Guerau-de-Arellano

This study shows PRMT5 in T cells drives Th17 responses and severe allergic airway inflammation in a mouse model of asthma.

DOI 10.4049/jimmunol.2100994

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 3, 2019

PRMT5 in T helper lymphocytes is essential for cholesterol biosynthesis-mediated Th17 responses and autoimmunity

L. M. Webb, S. Sengupta, C. Edell…·M. Guerau-de-Arellano

This study shows PRMT5 is essential for Th17 differentiation and autoimmunity by enhancing cholesterol biosynthesis and ROR-gamma t activation.

DOI 10.1101/792788

mouseexperimental assay

𝕏 PostBluesky