Author

M. Hefti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

B. Chen· 1 shared B. London· 1 shared C. A. Marcinkiewcz· 1 shared C. Brenner· 1 shared D.-F. Dai· 1 shared E. D. Abel· 1 shared G. P. Selvakumar· 1 shared J.-Y. Yoon· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPathology

B. Chen

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Author profile →

2 papers

Recent·Most cited

Behavioral dysregulation and monoaminergic deficits precede memory impairments in human tau-overexpressing (htau) mice

K. M. Khan, G. P. Selvakumar, N. Balasubramanian, R. Wang, S. Pierson, M. Hefti, C. A. Marcinkiewcz

This study shows that depressive-like behaviors and monoaminergic deficits occur before memory impairments in htau mice, suggesting early tau pathology impacts serotonergic neurons.

bioRxiv · Apr 3, 2022Animal Behavior & Cognition

Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome

J.-Y. Yoon, N. Daneshgar, Y. Chu, B. Chen, M. Hefti, K. Irani, L.-S. Song, C. Brenner, E. D. Abel, B. London, D.-F. Dai

This study shows that metabolic rescue with nicotinamide riboside improves mitochondrial encephalo-cardiomyopathy in mouse and human iPSC models of Leigh syndrome.

bioRxiv · Jan 4, 2022Pathology