Author

L.-S. Song

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:metabolism & bioenergetics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:electrophysiology· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

E. D. Abel· 4 shared B. Chen· 3 shared J. Streeter· 3 shared D. Hall· 2 shared D.-F. Dai· 2 shared R. O. Pereira· 2 shared A. Hinton· 1 shared A. Marshall· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersPhysiology

E. D. Abel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hepatic IRE1 Protects Against Septic Cardiac Failure

M. Li, R. R. Berton, Q. Qian, J. A. Maschek, B. Chen, E. Barroso, A. Rauckhorst, T. S. Griffith, E. B. Taylor, J. E. Cox, V. P. Badovinac, G. S. Hotamisligil, L.-s. Song, L. Yang

This study shows that hepatic IRE1 protects against septic cardiac failure by maintaining lipid metabolic balance, independent of inflammation.

bioRxiv · Mar 14, 2023 · PreprintPathology

Cardiac MAO-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control

Q. Shi, H. Malik, J. Streeter, J. Wang, R. Huo, R. M. Crawford, J. C. Shih, B. Chen, D. Hall, E. D. Abel, L.-S. Song, E. J. Anderson

This study shows that inhibiting MAO-A in cardiomyocytes reduces arrhythmias by improving diastolic calcium control following catecholamine stress.

bioRxiv · Sep 29, 2022Physiology

ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

A. Hinton, P. Katti, M. Mungai, D. Hall, O. Koval, J. Shao, Z. Vue, E. G. Lopez, R. Rostami, K. Neikirk, J. Ponce, J. Streeter, B. Schickling, S. Bacevac, C. Grueter, , E. D. Abel

This study shows that OPA1 deficiency in skeletal muscle increases MERC formation via ATF4, affecting calcium exchange and mitochondrial-ER tethering.

bioRxiv · Sep 12, 2022Biophysics

Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome

J.-Y. Yoon, N. Daneshgar, Y. Chu, B. Chen, M. Hefti, K. Irani, L.-S. Song, C. Brenner, E. D. Abel, B. London, D.-F. Dai

This study shows that metabolic rescue with nicotinamide riboside improves mitochondrial encephalo-cardiomyopathy in mouse and human iPSC models of Leigh syndrome.

bioRxiv · Jan 4, 2022Pathology

Cardiac Specific Overexpression of Transcription Factor EB (TFEB) in Normal Hearts Induces Pathologic Cardiac Hypertrophy and Lethal Cardiomyopathy

H. C. Kenny, E. T. Weatherford, G. V. Collins, C. Allamargot, T. Gesalla, K. Zimmerman, H. Goel, J. M. McLendon, D.-F. Dai, T. Romac, J. Streeter, D. Abhinav, R. O. Pereira, J. Sharafuddin, L.-S. Song, E. D. Abel

This study shows that cardiac-specific overexpression of TFEB leads to pathologic hypertrophy and lethal cardiomyopathy through mitochondrial dysfunction and fibrosis.

bioRxiv · Feb 16, 2021 · PreprintCell Biology