Author

M. Herwig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. G. McKee· 1 shared A. Mengozzi· 1 shared A. Tedman· 1 shared B. Pockrass· 1 shared C. P. Kuntz· 1 shared E. F. McDonald· 1 shared E. Gorica· 1 shared F. J. Roushar· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. G. McKee

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Chromatin Remodeling by the Histone Methyltransferase SETD2 Drives Lipotoxic Injury in Cardiometabolic Heart Failure with Preserved Ejection Fraction

S. Ambrosini, S. Costantino, S. A. Mohammed, E. Gorica, M. Herwig, L. van Heerebeek, A. Mengozzi, G. Karsai, T. Hornemann, O. Dzemali, F. Ruschitzka, N. Hamdani, F. Paneni

This study shows that SETD2 promotes lipotoxic injury in cHFpEF by regulating SREBP1 and lipid metabolism, and its inhibition improves cardiac function.

bioRxiv · Jul 25, 2024 · PreprintPhysiology

Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant

P. Carmody, F. J. Roushar, A. Tedman, W. Wang, M. Herwig, M. Kim, E. F. McDonald, K. Noguera, J. Wong-Roushar, J.-L. Poirier, N. Zelt, B. Pockrass, A. G. McKee, C. P. Kuntz, S. V. Raju, , J. P. Schlebach

This paper identifies an RNA structure in the CFTR transcript that promotes ribosomal frameshifting and premature termination, enhancing the function and pharmacological rescue of the misfolded {Delta}F508 CFTR variant.

bioRxiv · May 2, 2023Biochemistry