Cancer BiologybioRxiv
Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer
L. Pedersen, P. Panahandeh, M. I. Siraji…·N. Halberg
This study identifies PAQR4 as a Golgi-localized ceramidase upregulated in breast cancer, whose depletion induces apoptosis by accumulating ceramides.
DOI 10.1158/0008-5472.can-19-3177