M. J. Pallen

Linking carbohydrate structure with function in the human gut microbiome using hybrid metagenome assemblies

This study uses hybrid metagenome assemblies to analyze how structurally distinct carbohydrates affect gut microbiome composition and function by identifying carbohydrate-degrading microbes and their enzymatic capabilities.

Genomic diversity of Escherichia coli isolates from healthy children in rural Gambia

This study sequenced E. coli isolates from healthy children in rural Gambia, finding most diversity comes from immigration rather than within-host evolution.

Within-Host Diversity and Vertical Transmission of Group B Streptococcus Among Mother-infant Dyads in The Gambia

The paper investigates GBS transmission from mothers to infants, finding vertical transmission and within-host diversity in one dyad.

Assembly of hundreds of novel bacterial genomes from the chicken caecum

The paper assembles 469 draft bacterial genomes from chicken caecal samples, identifying 460 novel strains, 283 novel species, and 42 novel genera, and shows breed- and diet-specific microbiomes in European chickens.

Restoration of wild-type motility to flagellin-knockout Escherichia coli

This study restores wild-type motility to flagellin-knockout E. coli by optimizing promoter, plasmid copy number, and induction strength.

Metagenomic profiling of ticks: identification of novel rickettsial genomes and detection of tick-borne canine parvovirus

The paper uses metagenomic sequencing to identify novel rickettsial genomes and detect tick-borne canine parvovirus in ticks collected from Palestine.

Giant flagellins form thick flagellar filaments in two species of marine γ-proteobacteria

The paper shows that two marine γ-proteobacteria produce thick flagellar filaments made from giant flagellins, revealing evolutionary mechanisms for their formation.