Structural Mechanisms of Actin Isoforms
A. S. Arora, H.-L. Huang, R. Singh…·A. Suchenko
The paper reports high-resolution structures of actin isoforms with native PTMs, revealing isoform-specific conformations and their functional implications.
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6 papers
Recent·Most cited
A. S. Arora, H.-L. Huang, R. Singh…·A. Suchenko
The paper reports high-resolution structures of actin isoforms with native PTMs, revealing isoform-specific conformations and their functional implications.
T. Hatano, T. C. Lim, I. Billault-Chaumartin…·M. K. BALASUBRAMANIAN
The paper develops mNeonGreen-tagged tropomyosin and nanobodies to visualize tropomyosin localization in yeast, revealing new structures and dynamics in actin cytoskeleton.
S. Palani, A. Suchenko, S. Ghosh…·D. V. Koester
This paper shows that the 'curly' domain from IQGAP proteins stabilizes curved actin filaments when anchored to lipid membranes, forming high-curvature rings and enabling contraction with myosin II.
S. M. Chin, T. Hatano, L. Sivashanmugam…·S. Jansen
This study shows that acetylation and arginylation of actin's N-terminus differentially regulate actin polymerization dynamics and remodeling by actin-binding proteins, affecting network architecture and assembly rates.
B. Chapa-y-Lazo, M. Hamanaka, A. Wray…·M. Mishima
This study identifies dynein-mediated removal of cortical myosin II as the mechanism for polar relaxation, which drives cytokinesis in C. elegans embryos.
J. C. Meadows, L. J. Messin, A. Kamnev…·J. B. A. Millar
The paper shows that competition between stabilizing and destabilizing kinesin complexes at microtubule plus tips regulates iMT length in fission yeast.