Author

S. Palani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 7 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:yeast· 6 Research Focus:cell signaling & trafficking· 5 Research Focus:cell type annotation· 5 Research Focus:development & morphogenesis· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Assay:imaging· 2

Frequent Co-Authors

A. Dhar· 4 shared M. Balasubramanian· 2 shared M. K. BALASUBRAMANIAN· 2 shared T. Hatano· 2 shared A. Haig· 1 shared A. Potter· 1 shared A. Roivainen· 1 shared A. S. Viji· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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4 shared papersCell Biology

A. Dhar

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Functional redundancy and formin-independent localization of tropomyosin isoforms in Saccharomyces cerevisiae

A. Dhar, B. VT, S. Biswas, J. Kumari, A. Sridhara, J. S. Brahmendra, S. Shekhar, S. Palani

This study shows that Tpm isoforms in yeast bind actin filaments independently of formin isoforms and exhibit functional redundancy in actin cable maintenance.

bioRxiv · Apr 4, 2024 · PreprintCell Biology

ALIBY: ALFA Nanobody-Based Toolkit for Imaging and Biochemistry in Yeast

D. Akhuli, A. Dhar, A. S. Viji, B. Bhojappa, S. Palani

ALIBY is a yeast-specific toolkit that enables live-cell imaging and biochemical applications using the ALFA tag/NbALFA system, offering improved signal-to-noise ratio and versatility.

bioRxiv · Jul 18, 2022Cell Biology

mNeonGreen-tagged fusion proteins and nanobodies reveal localization of tropomyosin to patches, cables, and contractile actomyosin rings in live yeast cells

T. Hatano, T. C. Lim, I. Billault-Chaumartin, A. Dhar, Y. Gu, T. Massam-Wu, S. Adhishesha, L. Springall, W. Scott, L. Sivashanmugam, M. Mishima, S. G. Martin, S. Oliferenko, S. Palani, M. K. BALASUBRAMANIAN

The paper develops mNeonGreen-tagged tropomyosin and nanobodies to visualize tropomyosin localization in yeast, revealing new structures and dynamics in actin cytoskeleton.

bioRxiv · May 19, 2022Cell Biology

IntAct: a non-disruptive internal tagging strategy to study actin isoform organization and function

M. C. van Zwam, A. Dhar, W. Bosman, W. van Straaten, S. Weijers, E. Seta, B. Joosten, S. Palani, K. van den Dries

The paper introduces IntAct, a non-disruptive internal tagging strategy for studying actin isoform organization and function in mammalian and yeast cells.

bioRxiv · Oct 25, 2021 · PreprintCell Biology

Characterisation of the Ubiquitin-ESCRT pathway in Asgard archaea sheds new light on origins of membrane trafficking in eukaryotes

T. Hatano, S. Palani, D. Papatziamou, R. Salzer, D. Souza, D. Tamarit, M. Makwana, A. Potter, A. Haig, W. Xu, D. Bellini, D. Townsend, D. Rochester, H. Hussain, T. Ettema, , M. Balasubramanian

This study characterizes the ubiquitin-ESCRT pathway in Asgard archaea, showing its pre-eukaryotic origin and evolutionary path through gene duplication.

bioRxiv · Aug 17, 2021Cell Biology

Calponin-Homology Domain mediated bending of membrane associated actin filaments

S. Palani, A. Suchenko, S. Ghosh, E. Ivorra-Molla, S. Clarke, M. K. Balasubramanian, D. V. Koester

This paper shows that the 'curly' domain from IQGAP proteins stabilizes curved actin filaments when anchored to lipid membranes, forming high-curvature rings and enabling contraction with myosin II.

bioRxiv · Jul 10, 2020Biophysics

Dynein collective behavior in mitotic nuclear positioning of Saccharomyces cerevisiae

K. Jain, N. Khetan, S. Palani, C. A. Athale

The paper quantifies dynein's role in nuclear positioning during yeast mitosis by modeling SPB mobility and estimating force requirements.

bioRxiv · Jun 23, 2020 · PreprintCell Biology

Radiosynthesis and Preclinical Evaluation of Ga-NOTA-Folate for PET Imaging of Folate Receptor βPositive Macrophages

O. Moisio, S. Palani, J. Virta, P. Elo, H. Liljenback, T. Tolvanen, M. Kakela, M. G. Miner, E. Atencio Herre, P. Marjamaki, T. Ord, M. Heinaniemi, M. Kaikkonen-Maatta, F. Zhang, M. Srinivasarao, , A. Roivainen

This paper develops and evaluates [68Ga]Ga-NOTA-folate (68Ga-FOL) as a PET tracer for imaging FR-{beta}-positive macrophages in atherosclerosis, showing high affinity and specificity.

bioRxiv · May 18, 2020Biochemistry

Genetic interaction between profilin and myosin II reveals a potential role for myosin II in actin filament disassembly in vivo

P. Zambon, S. Palani, S. S. Jadhav, P. Gayathri, M. BALASUBRAMANIAN

The paper identifies a genetic interaction between profilin and myosin II in fission yeast, suggesting myosin II's role in actin filament disassembly and turnover.

bioRxiv · Apr 3, 2020Cell Biology