Author

M. K. Bhasin

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. E. Thomas· 1 shared N. R. Cheemarla· 1 shared R. Ganesan· 1 shared S. S. Bhasin· 1 shared U. Krishnan· 1 shared V. P. Sukhatme· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

B. E. Thomas

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1 paper

Recent·Most cited

Taxane chemotherapy leads to breast cancer dormancy escape by stromal injury mediated IL-6/MAP2K signaling

R. Ganesan, S. S. Bhasin, U. Krishnan, B. E. Thomas, N. R. Cheemarla, M. K. Bhasin, V. P. Sukhatme

This study shows that taxane chemotherapy induces stromal injury, releasing IL-6 and G-CSF that promote cancer dormancy escape via MEK/ERK signaling, and suggests targeting these cytokines or pathways to prevent recurrence.

bioRxiv · Jul 10, 2022 · PreprintCancer Biology