Enrichment of allelic editing outcomes by Prime Editing in iPS cells
R. Niwa, T. Matsumoto, A. Y. Liu, M. Kawato, T. Kondo, K. Tsukita, H. Inoue, T. L. Maurissen, K. Woltjen
This study compares Cas9 and Prime Editing (PE) in human iPS cells, showing PE's superior precision and demonstrating how sorting by PE expression affects allelic editing outcomes.
bioRxiv · Mar 19, 2024 · PreprintBioengineering