R. Niwa

The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster

This study identifies the seminal vesicle as a JH-responsive tissue in Drosophila, showing JH-induced gene expression and metabolic regulation.

Enrichment of allelic editing outcomes by Prime Editing in iPS cells

This study compares Cas9 and Prime Editing (PE) in human iPS cells, showing PE's superior precision and demonstrating how sorting by PE expression affects allelic editing outcomes.

Bacterial composition changes in canine plaque over periodontal disease severity and daily care practices

This study examines how bacterial composition in canine plaque changes with periodontal disease severity and daily care practices, finding increased Porphyromonas and decreased Conchiformibius with disease progression and improved outcomes with dental gel brushing.

A dark matter in sake brewing: Origin of microbes producing a Kimoto-style fermentation starter

This study identifies the microbial sources in Kimoto-style sake fermentation by analyzing environmental samples and fermentation starters.

A unique case in which Kimoto-style fermentation was completed with Leuconostoc as the dominant genus without transitioning to Lactobacillus.

The paper characterizes a unique Kimoto-style fermentation process where Leuconostoc dominates without transitioning to Lactobacillus, differing from previously reported microbial patterns.

Female reproductive dormancy in Drosophila melanogaster is regulated by DH31-producing neurons projecting into the corpus allatum

This study identifies DH31-producing neurons projecting to the corpus allatum as essential for regulating reproductive dormancy in Drosophila by suppressing juvenile hormone biosynthesis.

The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

This study identifies Neuropeptide F (NPF) in Drosophila as a sugar-responsive incretin-like hormone that regulates lipid metabolism via glucagon-like and insulin-like hormones.

A population of neurons that produce hugin and express the diuretic hormone 44 receptor gene projects to the corpora allata in Drosophila melanogaster

This study identifies hugin-producing neurons that project to the corpora allata in Drosophila melanogaster and express the Dh44 receptor gene, revealing a neuronal pathway involved in JH regulation.

An integrated approach unravels a crucial structural property for the function of the insect steroidogenic Halloween protein Noppera-bo

This paper determines the structure of the insect steroidogenic Halloween protein Noppera-bo and identifies a conserved residue critical for its function.

Practical and safe method of cryopreservation for clinical application of human adipose-derived mesenchymal stem cells without a programmable freezer or serum

This study develops a practical cryopreservation method for human ADSCs without a programmable freezer or serum, showing viability over 18 months at -150°C with specific cryoprotectants.