H. Inoue

Investigation of host plant contact with Diaphorina citri (Hemipreta: Psyllidae) by detecting D. citri-derived environmental DNA

This paper develops a method to detect Diaphorina citri-derived environmental DNA in host plants to trace psyllid contact and improve citrus greening disease monitoring.

Legionella uses host Rab GTPases and BAP31 to create a unique ER niche

This study shows Legionella pneumophila transforms the host ER membrane into a distinct rER niche using Rab GTPases and BAP31.

Enrichment of allelic editing outcomes by Prime Editing in iPS cells

This study compares Cas9 and Prime Editing (PE) in human iPS cells, showing PE's superior precision and demonstrating how sorting by PE expression affects allelic editing outcomes.

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics

This study identifies Atf3 as a key regulator of transition from compensation to dysfunction in female mitochondrial cardiomyopathy using single-cell transcriptomics.

Progressive spreading of DNA methylation in the GSTP1 promoter CpG island across transitions from precursors to invasive prostate cancer

The paper examines DNA methylation patterns in the GSTP1 promoter across prostate cancer progression stages and finds increasing methylation from normal to cancerous lesions.

Prolonged exposure to hypergravity increases number and size of cells and enhances lignin deposition in the stem of Arabidopsis thaliana (L.) Heynh.

Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist

This study identifies KSI-6666 as a pseudoirreversible S1PR1 antagonist that suppresses inflammation through interaction with a methionine residue.

Zinc-binding motif acts as an oxidative stress sensor to regulate TRPM7 channel activity

This study identifies the zinc-binding motif in TRPM7 as critical for oxidative stress sensing and Mg2+-dependent regulation of channel activity.

Erythropoietin production?by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation

This study develops a Western blot method with deglycosylation to detect Epo and ESAs in urine and plasma, showing the kidney as the main site of Epo production under hypoxia.

The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER-Golgi contact sites

The paper shows SCAP facilitates CARTS biogenesis at ER-Golgi contact sites by regulating cholesterol and PI4P exchange under cholesterol-fed conditions.

An integrated approach unravels a crucial structural property for the function of the insect steroidogenic Halloween protein Noppera-bo

This paper determines the structure of the insect steroidogenic Halloween protein Noppera-bo and identifies a conserved residue critical for its function.