Restoring vascular endothelial autophagic flux reduces atherosclerotic lesions
S. Chatterjee, M. Kheloufi, S. M. I. Mazlan, X. Loyer, T. A. McKinsey, C. Boulanger, P.-M. Coly
This study shows that inhibiting HDAC6 restores autophagic flux in endothelial cells under low shear stress, reducing atherosclerotic lesion formation.
bioRxiv · May 6, 2021 · PreprintPathology