Piezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells
M. Kuriyama, H. Hirose, T. Masuda, M. Shudou, J. V. V. Arafiles, M. Imanishi, M. Maekawa, Y. Hara, S. Futaki
The paper shows Yoda1 inhibits macropinocytosis and cancer cell proliferation by activating Piezo1, which regulates Ca2+ influx and KCa3.1 channel activity.
bioRxiv · May 14, 2021 · PreprintCell Biology