Aberrant accumulation of NIK promotes tumorigenicity by dysregulating post-translational modifications in breast cancer
Y. Hayashi, J. Nakayama, M. Yamamoto, M. Maekawa, S. Watanabe, S. Higashiyama, J.-i. Inoue, Y. Yamamoto, K. Semba
This study identifies NIK upregulation in breast cancer due to translational dysregulation, which promotes tumorigenicity by activating the non-canonical NF-κB pathway.
bioRxiv · Aug 27, 2021 · PreprintCancer Biology