Novel cytokinetic ring components drive negative feedback in cortical contractility
K. Rehain-Bell, M. E. Werner, A. Doshi, D. B. Cortes, A. Sattler, T. T. Vuong-Brender, M. Labouesse, A. S. Maddox
This study identifies GCK-1 and CCM-3 as novel cytokinetic ring components that form a negative feedback loop to regulate RhoA-mediated actomyosin contractility during cytokinesis and zygote polarization.
bioRxiv · May 3, 2020Cell Biology