A novel bacteriophage with broad host-range against Clostridioides difficile ribotype 078 elucidates the phage receptor.
M. J. Whittle, T. W. Bilverstone, R. J. van Esveld, A. C. Lücke, M. M. Lister, S. Kuehne, N. P. Minton
This study isolates four novel bacteriophages against C. difficile, identifies SlpA as the receptor for one phage with broad host-range activity against RT 078 strains, and suggests a strategy for developing a broad-spectrum phage cocktail.
bioRxiv · May 26, 2021Microbiology