Author

M. M. Mader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. M. Watson· 1 shared C. A. Zepeda-Velazquez· 1 shared C. Dela Sena· 1 shared C. H. Arrowsmith· 1 shared D. Barsyte-Lovejoy· 1 shared D. McLeod· 1 shared F. Li· 1 shared F. Meng· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

B. M. Watson

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1 paper

Recent·Most cited

A First-in-class, Highly Selective and Cell-active AllostericInhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

Y. Shen, F. Li, M. Szewczyk, L. Halabelian, I. Chau, M. S. Eram, C. Dela Sena, K.-S. Park, F. Meng, H. Chen, H. Zeng, D. McLeod, C. A. Zepeda-Velazquez, R. M. Campbell, M. M. Mader, , J. Jin

This paper reports the discovery of a first-in-class, highly selective allosteric inhibitor of PRMT6, SGC6870, with potent activity and selectivity in vitro and in cells.

bioRxiv · Dec 4, 2020 · PreprintBiochemistry