Author

M. Machino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. E. Dulcey· 1 shared A. N. Nilson· 1 shared D. R. Sibley· 1 shared H. D. Lim· 1 shared J. H. Woods· 1 shared J. J. Marugan· 1 shared J. R. Lane· 1 shared J. W. Bertz· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. E. Dulcey

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1 paper

Recent·Most cited

Identification and Characterization of ML321: a Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity

R. B. Free, A. N. Nilson, N. M. Boldizsar, T. Doyle, R. M. Rodriguiz, V. M. Pogorelov, M. Machino, K. H. Lee, J. W. Bertz, J. Xu, H. D. Lim, A. E. Dulcey, R. H. Mach, J. H. Woods, J. R. Lane, , D. R. Sibley

This paper develops ML321, a highly selective D2 dopamine receptor antagonist, showing efficacy in animal models predictive of atypical antipsychotic activity with fewer side effects.

bioRxiv · Nov 14, 2022Pharmacology & Toxicology