Author

M. Machyna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. Courchaine· 2 shared A. E. Barentine· 1 shared A. Patel· 1 shared A. Qin· 1 shared G. Biancon· 1 shared G. Viero· 1 shared H. Lin· 1 shared J. Bewersdorf· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

E. Courchaine

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Coilin oligomerization and remodeling by Nopp140 reveals a hybrid assembly mechanism for Cajal bodies

E. Courchaine, M. Machyna, K. Straube, S. Sauyet, J. Enright, K. Neugebauer

This study identifies coilin's N-terminal domain oligomerization and Nopp140's role in remodeling coilin oligomers to form Cajal bodies.

bioRxiv · Aug 1, 2021 · PreprintCell Biology

Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies

G. Biancon, P. Joshi, J. T. Zimmer, T. Hunck, Y. Gao, M. D. Lessard, E. Courchaine, A. E. Barentine, M. Machyna, V. Botti, A. Qin, R. Gbyli, A. Patel, Y. Song, L. Kiefer, , S. Halene

This study uses multi-omics profiling to analyze U2AF1 mutations in myeloid malignancies, revealing altered RNA binding, splicing, and stress granule formation.

bioRxiv · Apr 22, 2021Cancer Biology