Author

M. Martynowycz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:electronic health records· 4 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1

Frequent Co-Authors

T. Gonen· 5 shared J. Hattne· 4 shared G. Jensen· 2 shared W. Zhao· 2 shared C. Gillman· 1 shared C. Glynn· 1 shared C.-T. Zee· 1 shared D. Gidalevitz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersBiochemistry

T. Gonen

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Author profile →

6 papers

Recent·Most cited

Electron-counting in MicroED

J. Hattne, M. Martynowycz, M. Clabbers, T. Gonen

This paper discusses the benefits of electron-counting detectors in MicroED, highlighting their ability to improve data recording speed and accuracy while reducing radiation damage concerns.

bioRxiv · Jun 29, 2023 · PreprintBiochemistry

Design and implementation of suspended drop crystallization

T. Gonen, C. Gillman, M. Martynowycz, W. J. Nicolas

This paper introduces a new crystal growth method called suspended drop crystallization, which allows for direct crystal growth on an EM grid and enables structure determination by MicroED.

IUCrJ · May 25, 2023Peer-reviewedBiochemistry

Subphase Material Stabilizes Films of Pulmonary Surfactant

K. Andreev, M. Martynowycz, I. Kuzmenko, W. Bu, S. B. Hall, D. Gidalevitz

The paper uses X-ray scattering to show that vesicles in the subphase enhance the stability of pulmonary surfactant monolayers by increasing ordered interfacial structures.

bioRxiv · Feb 27, 2020 · PreprintBiophysics

Qualitative analyses of polishing and pre-coating FIB milled crystals for MicroED

M. Martynowycz, W. Zhao, J. Hattne, G. Jensen, T. Gonen

This study evaluates polishing and pre-coating techniques for FIB-milled crystals in MicroED, finding that platinum pre-coating and polishing improve signal-to-noise ratio, resolution, and refinement statistics.

bioRxiv · Apr 18, 2019Biochemistry

Collection of continuous rotation MicroED Data from Ion Beam Milled Crystals of Any Size

M. Martynowycz, W. Zhao, J. Hattne, G. Jensen, T. Gonen

This paper introduces a method to prepare protein crystals for continuous rotation MicroED using ion beam milling, eliminating the need for blotting optimization.

bioRxiv · Sep 24, 2018Biochemistry

Analysis of global and site-specific radiation damage in cryo-EM

J. Hattne, D. Shi, C. Glynn, C.-T. Zee, M. Gallagher-Jones, M. Martynowycz, J. Rodriguez, T. Gonen

The paper analyzes radiation damage in cryo-EM using MicroED, finding similar damage dynamics to X-ray crystallography, including metal ion perturbation and disulfide bond breaking.

bioRxiv · Feb 1, 2018Biochemistry