Author

C. Glynn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C.-T. Zee· 3 shared M. Gallagher-Jones· 3 shared J. A. Rodriguez· 2 shared T. Gonen· 2 shared C. G. Santiago· 1 shared C. Lin· 1 shared C. Millan· 1 shared D. Cascio· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

C.-T. Zee

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Author profile →

4 papers

Recent·Most cited

Biologically Driven In Vivo Occlusion Design Provides a Reliable Experimental Glaucoma Mouse Model

E. Hong, R. Yang, Q. Wang, F. Tian, R. Donahue, X. Li, C. Glynn, S. Tsekov, C. Lin, M. Xiong, S. Huang, S. Zhou, L. Yao, J. Tan, Y. Wang, , Q. Wang

This paper develops a biologically inspired microbead platform for inducing chronic ocular hypertension in mice, leading to retinal ganglion cell loss and visual pathway impairment.

bioRxiv · Jan 18, 2024 · PreprintBiophysics

Fragment-based ab initio phasing of peptidic nanocrystals by MicroED

L. Richards, M. D. Flores, C. Millan, C.-T. Zee, C. Glynn, M. R. Sawaya, M. Gallagher-Jones, R. Borges, I. Uson, J. A. Rodriguez

This paper introduces a fragment-based method for de novo structure determination of peptidic nanocrystals using MicroED, enabling the solution of previously intractable structures.

bioRxiv · Sep 13, 2021Biochemistry

Homochiral and racemic MicroED structures of a peptide from the ice nucleation protein InaZ

C.-T. Zee, C. Glynn, M. Gallagher-Jones, J. Miao, C. G. Santiago, D. Cascio, T. Gonen, M. Sawaya, J. A. Rodriguez

The paper determines homochiral and racemic structures of a peptide from InaZ using MicroED, revealing amyloid-like protofibrils with distinct chiral arrangements.

bioRxiv · Nov 19, 2018Biochemistry

Analysis of global and site-specific radiation damage in cryo-EM

J. Hattne, D. Shi, C. Glynn, C.-T. Zee, M. Gallagher-Jones, M. Martynowycz, J. Rodriguez, T. Gonen

The paper analyzes radiation damage in cryo-EM using MicroED, finding similar damage dynamics to X-ray crystallography, including metal ion perturbation and disulfide bond breaking.

bioRxiv · Feb 1, 2018Biochemistry