Author

M. Mei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

S. P. Diggle· 3 shared X. Tan· 2 shared Y. Wang· 2 shared B. Xu· 1 shared C. Wang· 1 shared C. Y. Zhao· 1 shared D. Huang· 1 shared D. Kurzeja-Edwards· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

S. P. Diggle

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A Combinatorial Strategy for HRV 3C Protease Engineering to Achieve the N-terminal Free Cleavage

L. Yi, G. Zhang, M. Mei, X. Fan, Y. Zhou, F. Zhang

This paper develops a combinatorial strategy to engineer HRV 3C protease for N-terminal free cleavage by expanding P1 specificity through structure-guided library design and high-throughput screening.

International Journal of Biological Macromolecules · Apr 1, 2024Peer-reviewedBioengineering

High recallability of memory B cells requires ZFP318-dependent transcriptional regulation of mitochondrial function

Y. Wang, W. Shao, X. Liu, Q. Liang, J. Lei, W. Shi, M. Mei, Y. Li, X. Tan, G. Yu, Y. Li, L. Zhang, H. Qi

This study shows that ZFP318 regulates mitochondrial function in memory B cells, enhancing their recallability and vaccine potency.

bioRxiv · Jun 11, 2023Immunology

High prevalence of lipopolysaccharide mutants and R2-Pyocin susceptible variants in Pseudomonas aeruginosa populations sourced from cystic fibrosis lung infections

M. Mei, P. Pheng, D. Kurzeja-Edwards, S. P. Diggle

This study examines R2-pyocin susceptibility in Pseudomonas aeruginosa from CF lung infections, finding high prevalence of susceptible variants and no correlation with LPS phenotypes.

bioRxiv · Apr 26, 2023 · PreprintMicrobiology

A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum Targeting

H. Fang, Y. Wang, L. Liu, K. Cheng, P. Li, Y. Tan, X. Hao, M. Mei, X. Xu, Y. Yao, F. Zan, L. Wu, Y. Zhu, B. Xu, D. Huang, , X.-W. Chen

The paper identifies a host metabolic pathway essential for coronavirus replication and shows that inhibiting it with Propranolol has broad antiviral effects.

bioRxiv · Dec 7, 2022 · PreprintCell Biology

Frequency of quorum sensing mutations in Pseudomonas aeruginosa strains isolated from different environments

K. O'Connor, C. Y. Zhao, M. Mei, S. P. Diggle

This study examines the frequency of quorum sensing mutations in Pseudomonas aeruginosa across different environments and finds that lasR mutations are common and not limited to infections, while pqs system proteins show high variability.

bioRxiv · Feb 22, 2021Microbiology

Heterogenous susceptibility to R-pyocin killing in populations of Pseudomonas aeruginosa sourced from cystic fibrosis lungs

M. Mei, J. Thomas, S. P. Diggle

The paper examines R-pyocin susceptibility in Pseudomonas aeruginosa populations from CF lungs, finding heterogeneous responses due to LPS core variations.

bioRxiv · Aug 5, 2020Microbiology