M. Mirzaei

Proteomic Profiling of Mesenchymal Stem Cell-Derived Extracellular Vesicles: Impact of Isolation Methods on Protein Cargo

This study compares protein cargo differences in mesenchymal stem cell-derived extracellular vesicles isolated by three methods, finding method-specific impacts on proteome composition and biological function.

Long-term Exposure to Methyl Jasmonate Increases Myrosinases TGG1 and TGG2 in Arabidopsis coi1 and myc2,3,4 Mutants

This study shows that long-term MeJA exposure increases TGG1 and TGG2 expression in Arabidopsis mutants, independent of the canonical JA pathway.

Aphid resistance segregates independently of cardiac glycoside and glucosinolate content in an Erysimum cheiranthoides (wormseed wallflower) F2 population

The paper examines aphid resistance in Erysimum cheiranthoides by analyzing the relationship between defensive metabolites and resistance traits in an F2 population.

Cardiac glycosides protect wormseed wallflower (Erysimum cheiranthoides) against some, but not all, glucosinolate-adapted herbivores

The paper investigates how cardiac glycosides in Erysimum cheiranthoides affect herbivore interactions, finding they protect against some but not all glucosinolate-tolerant herbivores.

Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics

The paper uses proteomics to compare DIPG cells in co-culture with brain organoids to control conditions, finding changes in adhesion, DNA synthesis, and dendrite growth pathways.

Arabidopsis MEB3 functions as a vacuolar transporter to regulate iron accumulation in roots

This study identifies MEB3 as a vacuolar iron transporter in Arabidopsis that regulates root-to-shoot iron distribution, showing its role in maintaining iron homeostasis under different iron conditions.

New Features Surrounding the Cdc42-Ste20 Module that Regulates MAP Kinase Signaling in Yeast

This study identifies new regulatory features of the Cdc42-Ste20 module in yeast MAPK signaling, including Ste20p turnover and a Ste20p-independent pathway branch.

Acropetal and basipetal cardenolide transport in Erysimum cheiranthoides (wormseed wallflower)

This study investigates cardenolide transport patterns in Erysimum cheiranthoides, finding maternal control of seed cardenolides and root cardenolide profiles determined by aboveground genotype.

Indole-3-glycerolphosphate synthase, a branchpoint for the biosynthesis of tryptophan, indole, and benzoxazinoids in maize

This study identifies three maize IGPS enzymes and their roles in tryptophan, indole, and benzoxazinoid biosynthesis, showing IGPS1 and IGPS3 are involved in defense while IGPS2 may contribute to tryptophan synthesis.

Proteomic and transcriptomic analysis of Microviridae {varphi}X174 infection reveals broad up-regulation of host membrane damage and heat shock responses

This study investigates the proteomic and transcriptomic response of E. coli to Microviridae {varphi}X174 infection, revealing broad up-regulation of host membrane damage and heat shock pathways.

Less Is More: A Mutation in the Chemical Defense Pathway of Erysimum cheiranthoides (Brassicaceae) Reduces Total Cardenolide Abundance but Increases Resistance to Insect Herbivores

This study shows a mutation in Erysimum cheiranthoides reduces total cardenolide abundance but increases resistance to two herbivore species.

Rapid and independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae)

The paper examines the evolution of chemical defenses in Erysimum plants, finding that ancestral and novel defenses evolved independently without trade-offs.