Author

M. Mladenov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

M. Way· 4 shared L. Cao· 3 shared A. Jegou· 2 shared A. Basant· 1 shared B. Guichard· 1 shared C. Moores· 1 shared F. Frey· 1 shared F. Ghasemi· 1 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiophysics

M. Way

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes

L. Cao, S. Huang, A. Basant, M. Mladenov, M. Way

This study shows CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes, with CK-869 uniquely affecting ArpC1B and Arp3-containing complexes, impacting phagocytosis and migration in macrophages.

bioRxiv · Nov 26, 2023Biochemistry

Regeneration of actin filament branches from the same Arp2/3 complex

F. Ghasemi, L. Cao, M. Mladenov, B. Guichard, M. Way, A. Jegou, G. Romet-Lemonne

The paper shows that Arp2/3 complex can re-nucleate actin branches without NPF activation after debranching, suggesting a self-repair mechanism for actin networks.

bioRxiv · Sep 22, 2023Biophysics

Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament

T. Liu, L. Cao, M. Mladenov, A. JEGOU, M. Way, C. Moores

This study reveals how cortactin stabilizes actin branches by interacting with activated Arp3 at the branch site, displacing other nucleation promoting factors.

bioRxiv · Aug 16, 2023Biophysics

Biomimetic actin cortices shape cell-sized lipid vesicles

L. Baldauf, F. Frey, M. A. Perez, M. Mladenov, M. Way, T. Idema, G. Koenderink

This study reconstitutes biomimetic actin cortices inside lipid vesicles to show how actin polymerization forces can both rigidify and deform membranes depending on nucleator distribution.

bioRxiv · Jan 15, 2023 · PreprintBiophysics