G. Koenderink

EMT-dependent cell-matrix interactions are linked to unjamming transitions in cancer spheroid invasion

This study investigates how EMT-dependent cell-matrix interactions influence unjamming transitions in cancer spheroid invasion using 3D invasion assays and quantitative image analysis.

Biomimetic actin cortices shape cell-sized lipid vesicles

This study reconstitutes biomimetic actin cortices inside lipid vesicles to show how actin polymerization forces can both rigidify and deform membranes depending on nucleator distribution.

Reconstituted branched actin networks sense and generate micron-scale membrane curvature

This paper shows that branched actin networks can sense and generate membrane curvature without relying on external factors, using reconstituted systems in giant unilamellar vesicles.

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

The paper identifies a MAP-like motif in Sept9 isoform 1 that drives septin-microtubule interaction and shows how HNA mutations disrupt this association.

Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

This study isolates recombinant human septin octamers with distinct SEPT9 isoforms and shows they form filament assemblies and bind actin filaments.

Weak catch bonds make strong networks

This paper shows that weak catch bonds in cytoskeletal networks enhance mechanical strength and deformability by enabling dissociation-on-demand, contrasting with the traditional strength-on-demand model.

Connecting the stimuli-responsive rheology of biopolymer hydrogels to underlying hydrogen-bonding interactions

This study connects the pH and temperature-responsive rheology of hyaluronan hydrogels to hydrogen-bonding interactions, showing how these bonds influence viscoelastic properties.

Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules

This study reconstitutes membrane tubulation using dynamic microtubules and proteins, revealing three motor-independent mechanisms for membrane remodeling.

Unraveling the response of a biomimetic actin cortex to electric pulses in vesicles

This study examines how an actin cortex in giant unilamellar vesicles affects electroporation and membrane resealing in response to electric pulses.