M. Momany

The Evolutionary Origins and Ancestral Features of Septins

This study investigates the evolutionary origins and ancestral features of septins by analyzing their phylogenetic distribution and structural evolution across eukaryotes.

Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States

This study identifies pan-azole- and multi-fungicide-resistant Aspergillus fumigatus in agricultural environments across 7 U.S. states.

Elevated mutation rates in the multi-azole resistant Aspergillus fumigatus cladedrives rapid evolution of antifungal resistance

This study identifies a mutation rate increase in a multi-azole resistant Aspergillus fumigatus clade, linking it to rapid antifungal resistance evolution.

Analysis of Cyp51 protein sequences shows 4 major Cyp51 gene family groups across Fungi

The paper identifies four major Cyp51 gene family groups across fungi using sequence analysis and phylogenetic trees, highlighting the conservation of Cyp51B in filamentous Ascomycota.

Sporulation environment drives phenotypic variation in the pathogen Aspergillus fumigatus

The paper shows that the environment where Aspergillus fumigatus spores are produced affects the germination variability among genetically identical spores.

Evidence for the agricultural origin of antimicrobial resistance in a fungal pathogen of humans

The paper identifies mutations in A. fumigatus that confer resistance to both clinical azoles and agricultural QoI fungicides, suggesting an agricultural origin for clinical resistance.

Septins coordinate cell wall integrity and lipid metabolism in a sphingolipid-dependent process

This study shows that septins in Aspergillus nidulans coordinate cell wall integrity and lipid metabolism through sphingolipid-dependent mechanisms, with distinct roles for core and noncore septins.