M. Onishi

The ERAD ubiquitin ligase Doa10 negatively regulates Atg32-mediated mitophagy

The paper shows that Doa10, an ERAD ubiquitin ligase, interacts with Atg32 to regulate its degradation, thereby negatively controlling mitophagy in yeast.

The Evolutionary Origins and Ancestral Features of Septins

This study investigates the evolutionary origins and ancestral features of septins by analyzing their phylogenetic distribution and structural evolution across eukaryotes.

Chloroplast Methyltransferase Homolog RMT2 is Involved in Photosystem I Biogenesis

The paper identifies RMT2 as a chloroplast methyltransferase homolog involved in photosystem I biogenesis in Chlamydomonas reinhardtii through a high-throughput O2 sensitivity screen.

A novel vaccine strategy using quick and easy conversion of bacterial pathogens to unnatural amino acid-auxotrophic suicide derivatives

This paper introduces a method to convert bacterial pathogens into live vaccines using unnatural amino acid-auxotrophic suicide derivatives, showing enhanced immunogenicity and safety.

Murine breast cancers disorganize the liver transcriptome in zonated manners

This study uses spatial transcriptomics to show that breast cancers disrupt liver zonation patterns, affecting specific metabolic and immune pathways in a zonated manner.

The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex

The paper shows the GET pathway regulates Atg32 phosphorylation and mitophagy by controlling Ppg1-Far localization and activity.

Control of division and microtubule dynamics in Chlamydomonas by cyclin B/CDKB1 and the anaphase-promoting complex

This study shows CYCB1 activates CDKB1 in Chlamydomonas to control mitosis and microtubule dynamics, with APC-dependent degradation of CYCB1 and regulation of mitotic events.

Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocyte accumulating hepatitis B surface antigen

Cleavage-furrow formation without F-actin in Chlamydomonas

This study shows that cleavage-furrow formation in Chlamydomonas can occur without F-actin or type-II myosin, suggesting an alternative mechanism involving microtubules.

Transfer of Septin Rings to Cytokinetic Remnants Directs Age-Sensitive ER stress Surveillance Cell Cycle Re-entry