Author

M. N. O'Connor

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ager· 1 shared A. Dritsoula· 1 shared A. H. Watson· 1 shared C. Camilli· 1 shared C. E. Bowers· 1 shared C. Pilotti· 1 shared D. M. Kallenberg· 1 shared J. George· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Ager

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1 paper

Recent·Most cited

Cancer BiologybioRxivOct 12, 2020

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

M. N. O'Connor, D. M. Kallenberg, R. Jackstadt…·J. Greenwood

This study shows that LRG1 promotes tumor vascular dysfunction and suppresses immunotherapy effectiveness, with its inhibition enhancing therapeutic outcomes in mouse cancer models.

DOI 10.1016/j.medj.2021.10.002

mouseexperimental assay

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