Author

R. Jackstadt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. J. Sansom· 2 shared A. Ager· 1 shared A. Dritsoula· 1 shared A. H. Watson· 1 shared A. Hedley· 1 shared A. J. McFarlane· 1 shared C. Camilli· 1 shared C. E. Bowers· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

O. J. Sansom

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Author profile →

2 papers

Recent·Most cited

Maturation, developmental site, and pathology dictate murine neutrophil function

J. B. G. Mackey, A. J. McFarlane, T. Jamieson, R. Jackstadt, X. L. Raffo-Iraolagoitia, J. Secklehner, X. Cortes-Lavaud, F. Fercoq, W. Clarke, A. Hedley, K. Gilroy, S. Lilla, J. Vuononvirta, G. J. Graham, K. De Filippo, , L. M. Carlin

This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.

bioRxiv · Jul 21, 2021 · PreprintImmunology

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

M. N. O'Connor, D. M. Kallenberg, R. Jackstadt, A. H. Watson, M. Alatsatianos, J. Ohme, C. Camilli, C. Pilotti, A. Dritsoula, C. E. Bowers, L. Dowsett, J. George, X. Wang, A. Ager, O. J. Sansom, , J. Greenwood

This study shows that LRG1 promotes tumor vascular dysfunction and suppresses immunotherapy effectiveness, with its inhibition enhancing therapeutic outcomes in mouse cancer models.

bioRxiv · Oct 12, 2020Cancer Biology