DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture
N. Eskndir, M. Hossain, M. L. Currey, M. Pho, Y. Berrada, A. D. Stephens
This study shows DNA damage reduces heterochromatin via ATM, leading to nuclear softening, blebbing, and rupture in MEF cells.
bioRxiv · May 24, 2024Cell Biology