Author

K. Chiu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Organism:mouse· 2

Frequent Co-Authors

A. D. Stephens· 3 shared Y. Berrada· 2 shared A. Burgess· 1 shared A. C. Fiumera· 1 shared A. Gunda· 1 shared A. Lavallee· 1 shared A. P. Vang· 1 shared A. Padam· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

A. D. Stephens

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

CTCF is essential for proper mitotic spindle structure and anaphase segregation

K. Chiu, Y. Berrada, N. Eskndir, D. Song, C. Fong, S. Naughton, T. Chen, S. Moy, S. Gyurmey, L. James, C. Ezeiruaku, C. Capistran, D. Lowey, V. Diwanji, S. Peterson, , A. D. Stephens

This study shows that CTCF is crucial for correct mitotic spindle structure and anaphase segregation, leading to abnormal nuclear morphology in interphase.

bioRxiv · Jan 9, 2023Cell Biology

Actin contraction controls nuclear blebbing and rupture independent of actin confinement

M. Pho, Y. Berrada, A. Gunda, A. Lavallee, K. Chiu, A. Padam, M. L. Currey, A. D. Stephens

This study shows that actin contraction drives nuclear blebbing and rupture independently of actin confinement, with lamin B1 playing a key role in chromatin decompaction phenotypes.

bioRxiv · Dec 1, 2022Cell Biology

Development and application of genetic ancestry reconstruction methods to study diversity of patient-derived models in the NCI PDXNet Consortium

B. J. Sanderson, P. Lott, K. Chiu, J. E. Quino, A. P. Vang, M. W. Lloyd, A. Srivastava, PDXNet Consortium, J. H. Chuang, L. G. Carvajal-Carmona

The paper develops a genetic ancestry pipeline to assess diversity in PDX models and finds overrepresentation of European ancestry models, highlighting gaps in minority representation for cancer research.

bioRxiv · Oct 24, 2022 · PreprintCancer Biology

Mapping mitonuclear epistasis using a novel recombinant yeast population

T. H. M. Nguyen, A. Tinz-Burdick, M. Lenhardt, M. Geertz, F. Ramirez, M. Schwartz, M. Toledano, B. Bonney, B. Gaebler, W. Liu, J. F. Wolters, K. Chiu, A. C. Fiumera, H. Fiumera

The paper maps mitonuclear epistasis in yeast by creating a novel recombinant population and identifies loci influencing mtDNA stability and mitotic growth.

bioRxiv · Aug 31, 2022Evolutionary Biology

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

A. R. Strom, R. J. Biggs, E. J. Banigan, X. Wang, K. Chiu, C. Herman, J. Collado, F. Yue, J. C. Ritland Politz, L. J. Tait, D. Scalzo, A. Telling, M. Groudine, C. P. Brangwynne, J. Marko, A. D. Stephens

This study shows HP1α crosslinks chromatin to maintain nuclear and mitotic chromosome mechanics, independent of histone methylation.

bioRxiv · Oct 9, 2020Biophysics

Mesenchymal stem cells protect retinal ganglion cells from degeneration via mitochondrial donation

D. JIANG, H. Feng, Z. Zhang, B. Yan, L. Chen, C. Ma, C. Li, S. Han, Y. Zhang, P. Chen, H.-F. Tse, Q. Fu, K. Chiu, Q. Lian

This study shows that mesenchymal stem cells (MSCs) protect retinal ganglion cells (RGCs) from degeneration by donating mitochondria, reducing inflammation, and preserving retinal function in a mouse model.

bioRxiv · Aug 19, 2018 · PreprintCell Biology