Author

M. Pinho-Schwermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

K. E. Huntington· 2 shared L. Zhang· 2 shared P. R. Srinivasan· 2 shared V. Tajiknia· 2 shared W. S. El-Deiry· 2 shared A. De Souza· 1 shared A. George· 1 shared B. A. Carneiro· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

K. E. Huntington

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2 papers

Recent·Most cited

Androgen receptor signaling blockade enhances NK cell-mediated killing of prostate cancer cells and sensitivity to NK cell checkpoint blockade

M. Pinho-Schwermann, C. Purcell, L. Carlsen, K. E. Huntington, P. R. Srinivasan, A. George, V. Tajiknia, W. MacDonald, L. Zhou, L. Zhang, A. De Souza, H. P. Safran, B. A. Carneiro, W. S. El-Deiry

This study shows that androgen receptor inhibitors enhance NK cell-mediated killing of prostate cancer cells and sensitivity to NKG2A checkpoint blockade by upregulating HLA-E expression.

bioRxiv · Nov 15, 2023 · PreprintCancer Biology

Synergistic anti-tumor activity, reduced pERK, and immuno-stimulatory cytokine profiles with 5-FU or ONC212 plus KRAS G12D inhibitor MRTX1133 in CRC and pancreatic cancer cells independent of G12D mutation

V. Tajiknia, M. Pinho-Schwermann, P. R. Srinivasan, L. Hernandez Borrero, L. Zhang, K. E. Huntington, W. S. El-Deiry

This study shows that MRTX1133, a KRAS G12D inhibitor, synergizes with 5-FU or ONC212 to reduce tumor cell viability and pERK in CRC and pancreatic cancer cells, regardless of KRAS mutation status.

bioRxiv · Sep 13, 2023Cancer Biology