Author

L. Carlsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Zhou· 2 shared W. El-Deiry· 2 shared A. A. Seyhan· 1 shared A. De Souza· 1 shared A. George· 1 shared A. M. Jamieson· 1 shared A. Navaraj· 1 shared A. R. D. Jordon· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

L. Zhou

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Androgen receptor signaling blockade enhances NK cell-mediated killing of prostate cancer cells and sensitivity to NK cell checkpoint blockade

M. Pinho-Schwermann, C. Purcell, L. Carlsen, K. E. Huntington, P. R. Srinivasan, A. George, V. Tajiknia, W. MacDonald, L. Zhou, L. Zhang, A. De Souza, H. P. Safran, B. A. Carneiro, W. S. El-Deiry

This study shows that androgen receptor inhibitors enhance NK cell-mediated killing of prostate cancer cells and sensitivity to NKG2A checkpoint blockade by upregulating HLA-E expression.

bioRxiv · Nov 15, 2023 · PreprintCancer Biology

miR-6883 downregulates HIF1α in colorectal and breast cancer cells

N. Jensen-Velez, L. Carlsen, W. El-Deiry

The paper shows miR-6883 reduces CDK4/6 and HIF1 in colorectal and breast cancer cells under normoxia and hypoxia, suggesting it as a potential therapeutic target for hypoxic cancers.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology

Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells

L. Zhou, K. Huntington, S. Zhang, L. Carlsen, E.-Y. So, C. Parker, I. Sahin, H. Safran, S. Kamle, C.-M. Lee, C.-G. Lee, J. A. Elias, K. S. Campbell, M. T. Naik, W. J. Atwood, , W. El-Deiry

This study shows MEK inhibitors reduce ACE2 and inflammatory cytokines, enhance NK cell activity, and block SARS-CoV-2 pseudovirus infection in human cells.

bioRxiv · Aug 2, 2020 · PreprintCell Biology

Pulmonary infection interrupts acute cutaneous wound healing through disruption of chemokine signals

M. J. Crane, Y. Xu, S. F. Monaghan, B. M. Hall, J. E. Albina, W. L. Henry, H. L. Tran, K. R. P. Chhabria, A. R. D. Jordon, L. Carlsen, A. M. Jamieson

This study shows that pulmonary infection impairs cutaneous wound healing by reducing chemokine signaling, which can be reversed by restoring chemokine levels.

bioRxiv · May 8, 2020 · PreprintImmunology