Cancer BiologybioRxivPreprint
Androgen receptor signaling blockade enhances NK cell-mediated killing of prostate cancer cells and sensitivity to NK cell checkpoint blockade
M. Pinho-Schwermann, C. Purcell, L. Carlsen…·W. S. El-Deiry
This study shows that androgen receptor inhibitors enhance NK cell-mediated killing of prostate cancer cells and sensitivity to NKG2A checkpoint blockade by upregulating HLA-E expression.