Author

M. Pitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

D. Ganesamoorthy· 2 shared L. Coin· 2 shared M. D. Cao· 2 shared A. Elliott· 1 shared C. S. Abboud· 1 shared D. Purcell· 1 shared D. Rawlinson· 1 shared D. Williamson· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

D. Ganesamoorthy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Direct RNA sequencing and early evolution of SARS-CoV-2

G. Taiaroa, D. Rawlinson, L. Featherstone, M. Pitt, L. Caly, J. Druce, D. Purcell, L. Harty, T. Tran, J. Roberts, N. Scott, M. Catton, D. Williamson, L. Coin, S. Duchene

The paper presents the first native RNA sequence of SARS-CoV-2, detailing its transcriptome and epitranscriptome, and infers genetic features and evolutionary rate.

bioRxiv · Mar 5, 2020 · PreprintMicrobiology

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

M. Pitt, M. D. Cao, M. Butler, S. Ramu, D. Ganesamoorthy, M. Blaskovich, L. Coin, M. Cooper

This study compares resistance development in XDR Klebsiella pneumoniae ST258 exposed to polymyxins and octapeptin C4, finding OctC4 induces less resistance and novel mutations.

bioRxiv · Apr 28, 2018Microbiology

Multifactorial Chromosomal Variants Regulate Polymyxin Resistance In Extensively Drug-Resistant Klebsiella pneumoniae

M. Pitt, A. Elliott, M. D. Cao, D. Ganesamoorthy, I. Karaiskos, H. Giamarellou, C. S. Abboud, M. A. T. Blaskovich, M. A. Cooper, L. J. M. Coin

This study identifies chromosomal variants in mgrB and phoQ genes that confer polymyxin resistance in XDR-Klebsiella pneumoniae isolates from Greece and Brazil.

bioRxiv · Oct 10, 2017Microbiology