Author

G. Taiaroa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:gene regulatory network inference· 3 Research Focus:host-pathogen & immune response· 3 Assay:long-read sequencing· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

D. A. Williamson· 5 shared G. M. Cook· 3 shared T. P. Stinear· 3 shared D. Rawlinson· 2 shared J. L. Porter· 2 shared L. Caly· 2 shared T. Tran· 2 shared Y. Wang· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

D. A. Williamson

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis

S. J. Pidot, S. Klatt, L. S. Ates, W. Frigui, F. Sayes, L. Majlessi, H. Izumi, I. R. Monk, J. L. Porter, V. Bennett-Wood, T. Seemann, A. Otter, G. Taiaroa, G. M. Cook, N. West, , T. P. Stinear

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

bioRxiv · Jan 23, 2024 · PreprintMicrobiology

A transmission chain linking Mycobacterium ulcerans with Aedes notoscriptus mosquitoes, possums and human Buruli ulcer cases in southeastern Australia

P. T. Mee, A. H. Buultjens, J. Oliver, K. Brown, J. C. Crowder, J. L. Porter, E. C. Hobbs, L. M. Judd, G. Taiaroa, N. Puttharak, D. A. Williamson, K. R. Blasdell, E. L. Tay, R. Feldman, M. O. Muzari, , S. E. Lynch

The paper investigates the transmission chain of Mycobacterium ulcerans between mosquitoes, possums, and humans in southeastern Australia, finding a significant association between M. ulcerans and Aedes notoscriptus mosquitoes.

bioRxiv · May 7, 2023 · PreprintMicrobiology

Rapid recall and de novo T cell responses during SARS-CoV-2 breakthrough infection

M. Koutsakos, A. Reynaldi, W. S. Lee, J. Nguyen, T. Amarasena, G. Taiaroa, P. Kinsella, K. C. Liew, T. Tran, H. E. Kent, H.-X. Tan, L. C. Rowntree, T. H. O. Nguyen, P. Thomas, K. Kedzierska, , J. A. Juno

This study examines T cell responses during SARS-CoV-2 breakthrough infections, showing rapid recall of memory T cells and a correlation between CD8+ T cell activation and viral clearance.

bioRxiv · Dec 19, 2022Immunology

Treatment history shapes the evolution of complex carbapenem-resistant phenotypes in Klebsiella spp.

T. Lithgow, T. Zhou, M. MCDONALD, N. Rosas, J. Wilksch, J. Barber, J. Li, Y. Wang, Z. Sun, A. Rocker, C. Webb, L. Perlaza-Jimenez, C. Stubenrauch, D. Vijaykrishn, J. Song, , Q. Bao

This study shows that treatment history influences the evolution of carbapenem resistance in Klebsiella by shaping the genetic loci involved and their fitness costs.

bioRxiv · Aug 30, 2022Microbiology

RNase HI depletion strongly potentiates cell killing by rifampicin in mycobacteria

A. Al-Zubaidi, C.-Y. Cheung, G. M. Cook, G. Taiaroa, V. Mizrahi, J. S. Lott, S. S. Dawes

This paper shows that reducing RNase HI activity in mycobacteria increases sensitivity to rifampicin, suggesting RNase HI as a target for new antibiotics.

bioRxiv · Jul 14, 2021Microbiology

Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection

J. J.- Y. Chang, D. Rawlinson, M. E. Pitt, G. Taiaroa, J. Gleeson, C. Zhou, F. L. Mordant, R. De Paoli-Iseppi, L. Caly, D. F. J. Purcell, T. P. Stinear, S. L. Londrigan, M. B. Clark, D. A. Williamson, K. Subbarao, L. J. M. Coin

This study examines SARS-CoV-2 transcriptional and epi-transcriptional dynamics using long-read sequencing in human and primate infection models, revealing distinct patterns of sgRNA regulation and modification.

bioRxiv · Dec 22, 2020Microbiology

Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment

K. C. Ma, T. D. Mortimer, A. L. Hicks, N. E. Wheeler, L. Sanchez-Buso, D. Golparian, G. Taiaroa, D. H. Rubin, Y. Wang, D. A. Williamson, M. Unemo, S. R. Harris, Y. H. Grad

This study identifies loss-of-function mutations in efflux pumps as a mechanism for increased antibiotic susceptibility in Neisseria gonorrhoeae cervical isolates.

Nature Communications · Aug 17, 2020Peer-reviewedMicrobiology

Direct RNA sequencing and early evolution of SARS-CoV-2

G. Taiaroa, D. Rawlinson, L. Featherstone, M. Pitt, L. Caly, J. Druce, D. Purcell, L. Harty, T. Tran, J. Roberts, N. Scott, M. Catton, D. Williamson, L. Coin, S. Duchene

The paper presents the first native RNA sequence of SARS-CoV-2, detailing its transcriptome and epitranscriptome, and infers genetic features and evolutionary rate.

bioRxiv · Mar 5, 2020 · PreprintMicrobiology

Cellular and structural basis of synthesis of the unique intermediate dehydro-F420-0 in mycobacteria

R. Grinter, B. Ney, R. Brammananth, C. K. Barlow, P. R. F. Cordero, D. L. Gillett, T. Izore, M. Cryle, L. Harold, G. M. Cook, G. Taiaroa, D. A. Williamson, A. C. Warden, J. G. Oakeshott, M. C. Taylor, , C. Greening

This study resolves the biosynthesis pathway of F420 in mycobacteria by showing phosphoenolpyruvate, not 2-phospholactate, is the precursor and identifies the structural mechanism of dehydro-F420-0 production.

bioRxiv · Feb 27, 2020Biochemistry