Author

M. R. Chastney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

C. Jorgensen· 2 shared D. Knight· 2 shared J. D. Humphries· 2 shared M. C. Jones· 2 shared M. J. Humphries· 2 shared A. Mironov· 1 shared C. Lawless· 1 shared C. R. Below· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

C. Jorgensen

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2 papers

Recent·Most cited

Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation

J. D. Humphries, J. Zha, J. Burns, J. A. Askari, C. R. Below, M. R. Chastney, M. C. Jones, A. Mironov, D. Knight, D. A. O'Reilly, M. J. Dunne, D. R. Garrod, C. Jorgensen, M. J. Humphries

This study identifies integrin α6β4 and hemidesmosomes as critical for PDAC cell proliferation and ECM organization, with implications for therapeutic targeting.

bioRxiv · Aug 19, 2021Cancer Biology

Definition of the fibroblast adhesome using multiplexed proximity biotinylation

M. R. Chastney, C. Lawless, J. D. Humphries, S. Warwood, M. C. Jones, D. Knight, C. Jorgensen, M. J. Humphries

The paper defines the fibroblast adhesome using multiplexed proximity biotinylation and identifies functional modules within integrin adhesion complexes.

bioRxiv · Jan 24, 2020Cell Biology